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Distinguishing local from systemic IGF-1 action A recurring theme in the muscle literature is that locally produced IGF-1 generated within the muscle in response to loading or expressed from a transgene appears especially effective at supporting hypertrophy and repair, potentially through autocrine and paracrine action on nearby satellite cells and fibers

The administration of resveratrol in ASD patients enhances the social impairment and ameliorates the behavioral hyperactivity and cognitive function